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Pauling’s last legacy: a unified theory of cardiovascular disease

24 Dec

Pauling’s last legacy: a unified theory of cardiovascular disease

Linus Carl Pauling (1901–1994) was an American chemist, peace activist, author and educator regarded as one of the most influential chemists in history. He was among the first scientists to work in the fields of quantum chemistry and molecular biology, and is the only individual to have won two unshared Nobel Prizes.

A paper submitted by Pauling to the Proceedings of the National Academy of Sciences and accepted for publication on June 11, 1991 was later revoked by the editor under questionable circumstances: “We are aware that this pullback was not the decision of an individual. It happened in the interest of those who are personally or economically dependent on the present dogma of human cardiovascular disease.”

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Chronic inflammation without heart disease among the Tsimane’

17 Dec

Chronic inflammation without heart disease among the Tsimane’

The Tsimane’ Health and Life History Project

The Tsimane’ are a population of some 9,000 forager-horticulturalists inhabiting a vast area of lowland forests, and savannas east of the Andes in the Bolivian Amazon. They live in about 80 small villages without running water or electricity, and make a living through swidden agriculture, hunting, fishing, gathering, and occasional wage labor.

The Tsimane’ offer some of the last remaining opportunities to study the effects of kin, culture, and ecology on aging in a small-scale, natural fertility, kin-based, subsistence society, and for this reason have been the focus of study by the UNM-UCSB Tsimane’ Health and Life History Project which began in 2001.

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An inflammatory review of atherosclerosis

18 Nov

An inflammatory review of atherosclerosis

Heart disease and cardiovascular disease (CVD) are synonymously used names to describe various diseases of the heart and blood vessels. Atherosclerosis is the lesser-known name of the underlying condition and common cause of CVD that results in symptoms such as heart attack, stroke, angina and peripheral vascular disease. As a condition that hardly existed before the 20th century, complications due to atherosclerosis now account for the majority of adult illness and deaths in the industrialised world, killing more people than cancer. Due to its asymptomatic nature and frequent under-diagnosis, the first symptom of atherosclerosis can often present without warning.

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